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What special precautions should I follow?
Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil ], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])—Higher blood levels of these medicines may occur, which may increase the chance of developing unwante effects. Your doctor may check the blood level of the tricyclic antidepressant, and may change the dose of either these medicines or Zoloft. Also, taking Zoloft with amitriptyline, clomipramine, or i mipramine may increase the chance of developing the serotonin syndrome

Management of Overdoses:

- hair loss
- changes in sex drive or ability
- drowsiness
- excessive tiredness
- difficulty falling asleep or staying asleep
- diarrhea
- vomiting
- rapid pou nding or irregular heartbeat
- upset stomach
- dizziness
- excitement
- tremor
- coma
- seizures
- hearing voices or seeing things that do not exist (hallucinating)
- unconsciousness
- fainting

Side Effects
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zoloft.

Zoloft may also cause mental or emotional symptoms such as:
- Abnormal dreams or thoughts, aggressiveness, exaggerated feeling of well-being, depersonalization ("unreal" feeling), hallucinat ions, impaired concentration, memory loss, paranoia, rapid mood shifts, suicidal thoughts, tooth-grinding, worsened depression

Many people lose a pound or two of body weight while taking Zolo ft. This usually poses no problem but may be a concern if your depression has already caused you to lose a great deal of weight.

Special Wanring
Autonomic Nervous System Disorders: - Infrequent: Flushing, mydriasis, increased saliva, cold clammy skin. Rare: Pallor.

How should this medicine be used?
Zoloft is available in capsule and oral concentrate forms. To prepare Zoloft oral concentrate, use the dropper provided. Measure out the amount of concentrate prescribed by your doctor and mix it with 4 ounces of water, ginger ale, lemon/lime soda, lemonade, or orange juice. (Do not mix the concentrate with any other type of beverage.) Drink the mixture immediately; do not prepare it in advance fo r later use. At times, a slight haze may appear after mixing, but this is normal.

Improvement with Zoloft may not be seen for several days to a few weeks. You should expect to keep taking it for at least several months.

Zoloft may make your mouth dry. For temporary relief suck a hard candy, chew gum, or melt bits of ice in your mouth.

What Is It
In addition, Zoloft is used in the treatment of obsessive-compulsive disorder--symptoms of which include unwanted thoughts that won't go away and an irresistible urge to keep repeating certain actions , such as hand-washing or counting. It is also prescribed for the treatment of panic disorder (unexpected attacks of overwhelming anxiety, accompanied by fear of their return), and for posttraumatic s tress disorder (re-experiencing a dangerous or life-threatening event through intrusive thoughts, flashbacks, and intense psychological distress).