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Before Using This Medicine
Breast-feedingˇXIt is not known whether Meridia passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. A mother w
ho is taking this medicine and who wishes to breast-feed should discuss this with her doctor.
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How should you take this medication?
Meridia comes as a capsule to take by mouth. It is usually taken once a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or ph
armacist to explain any part you do not understand.
Take Meridia exactly as directed. Meridia can be habit forming. Do not take a larger dose, take it more often, or for a longer period than
your doctor tells you to.
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Side Effects
Use Meridia with caution if you have uncontrolled high blood pressure; it could make the problem worse. Avoid Meridia completely if you've had a stroke or suffer from heart disease, heart failure, or
irregular heartbeat. Also avoid it if you have severe kidney or liver problems; the drug has not been tested under these conditions. Seizures are a rare, but possible, side effect. If you've had seizu
res in the past, use Meridia with caution. If you have a seizure while taking the drug, stop using it and call your doctor immediately.
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Precautions while Using this Medicine
Do not take Meridia while you are taking or within 2 weeks of taking medicines with monoamine oxidase (MAO) inhibitor activity , such as isocarboxazid (e.g., Marplan), phenelzine (e.g., Nardil), proca
rbazine (e.g., Matulane), selegiline (e.g., Eldepryl), or tranylcypromine (e.g., Parnate). Do not take an MAO inhibitor within 2 weeks of taking Meridia. To do so may cause severe seizures, extremely
high blood pressure, or a life-threatening adverse effect called the serotonin syndrome.
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MERIDIA is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of MERIDIA after a few weeks of treatment, which
When you are taking Meridia, it is especially important that your health care professional know if you are taking any of the following:
- Monoamine oxidase (MAO) inhibitor activity (isocarbo
xazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])ˇX Do not take Meridia while you are taking or within 2 wee
ks of taking an MAO inhibitor, and do not take an MAO inhibitor within 2 weeks of taking Meridia . If you do, you may develop severe seizures, extremely high blood pressure, or the serotonin syndrome.
Allow at least 2 weeks to pass between taking one of these medicines (Meridia or an MAO inhibitor) and taking the other
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Why is this drug prescribed?
Patients treated with MERIDIA while on a reduced calorie diet showed significant weight loss during the first 6 months of treatment, and significant weight loss was maintained for one year. In one 12-
month study, the average weight loss in patients taking MERIDIA, 10 mg daily, was about 10 lbs. and in those taking 15 mg daily was about 14 lbs. The average weight loss in persons on only a reduced c
alorie diet alone was 3 1/2 lbs. Thus, MERIDIA is proven effective therapy for the obese patient who needs to loose weight to decease morbidity. Nonetheless, the magnitude of the weight loss will ulti
mately depend on the degree of concomitant caloric restriction and the concomitant use of a graded exercise program.
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