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DRUG ABUSE AND DEPENDENCE :
Although BuSpar does not intensify the effects of alcohol, it is best to avoid alcohol while taking this medication.
If BuSpar is taken with certain other drugs, the effects of either can be
increased, decreased, or altered. It is especially important to check with your doctor before combining BuSpar with the following:
- The blood-thinning drug Coumadin
- Haloperidol (Hal
dol)
- MAO inhibitors (antidepressant drugs such as Nardil and Parnate)
- Trazodone (Desyrel)
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Possible Side Effect
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your
doctor as soon as possible if any of the following side effects occur:
Chest pain; confusion; fast or pounding heartbeat; fever; incoordination; mental depression; muscle weakness; num
bness, tingling, pain, or weakness in hands or feet; skin rash or hives; stiffness of arms or legs; sore throat; uncontrolled movements of the body
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How to Use
Take BuSpar exactly as prescribed. Do not be discouraged if you feel no immediate effect. The full benefit of this drug may not be seen for 1 to 2 weeks after you start to take it.
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Other Medicines
In vitro, buspirone does not displace tightly bound drugs like phenytoin, propranolol and warfarin from serum proteins. However, there has been 1 report of prolonged prothrombin time when buspirone wa
s added to the regimen of a patient treated with warfarin. The patient was also chronically receiving phenytoin, phenobarbital, digoxin and Synthroid. In vitro, buspirone may displace less firmly boun
d drugs like digoxin. The clinical significance of this property is unknown.
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Symptoms of overdose may include:
- upset stomach
- vomiting
- dizziness
- drowsiness
- blurred vision
- upset stomach
- vomiting
- dizziness
- drowsiness
- blurred vision
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Adverse Effects
CNS:
Dizziness, headache, drowsiness, lightheadedness, insomnia, fatigue, nervousness, decreased concentration, excitement, depression, confusion, nightmares/vivid dreams, anger/hostility. Infrequ
ently (<1%) depersonalization, noise intolerance, euphoria/feeling high, dissociative reaction, fear, loss of interest, dysphoria, hallucinations, seizures, suicidal thoughts. Rarely, slurred speech,
claustrophobia, cold intolerance, stupor, psychosis.
Neurologic:
Paresthesia, weakness, incoordination, tremor, numbness. Infrequently, muscle cramps and spasms, rigid/stiff muscles, involu
ntary movements, akathisia, slowed reaction time. Rarely, tingling of limbs, stiff neck, rigidity of jaw, ataxia.
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